![]() ![]() We report a unique case of a 10-year-old female with previously undiagnosed and untreated CF presenting with abdominal pain, vomiting, and obstructive jaundice. Many mutations in the CFTR gene can lead to mild cases of CF, which may delay diagnosis and treatment ( 3, 5). ![]() In a multicenter study of 155 patients, mutations in the CF transmembrane conductance regulator (CFTR) gene were reported in 34% and 23% of acute recurrent pancreatitis and chronic pediatric pancreatitis patients, respectively ( 4). Pancreatitis can be the presenting symptom in children with CF ( 3). CF is a heterogeneous disease with significant variability in organ-specific clinical manifestations ( 3). Although there are many causes of pancreatitis in children, genetic mutations are among the most common etiologies, with cystic fibrosis (CF) being one of the more frequently identified genetic diseases. Pancreatic stone formation is related to chronic pancreatitis (CP). However, obstructive jaundice in the absence of biliary abnormalities is uncommon ( 2). Ductal obstruction can lead to destruction and atrophy of the pancreatic parenchyma, and patients typically present with abdominal pain and emesis ( 1). Match 3 or more stones from the same color to connect them and make them explode! Just like a puzzle inside a mine.Pancreatic lithiasis, also known as calcifying pancreatitis, is characterized by the formation of stones in the pancreatic duct or its branches. Accumulate a good loot and then sell it in Joe's shop to get money for buying new equipment for your next expedition.īut beware of the rocks in the depths of the mine, dig carefully or they will crush you! Use your pickaxe to pick your way through to find a way to match the stones together. ![]() Here down in the mine life is simple: Digging day and night and trying to find all the gold you can (and if you're lucky, a couple of hidden treasures). Take your new pickaxe, put on your helmet and let's enter the mine! Enjoy the best mining game out there and explore an infinite mine full of treasures, dangers and puzzles that only a true expert miner can solve! ![]()
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